The 33-year-old Republic of Ireland international has been with the Suffolk club on a permanent basis for three years following a move from Celtic.
Murphy, a former Sunderland player, has made four appearances for Ipswich this term but is yet to get on the scoresheet.
Newcastle boss Rafael Benitez wants Murphy to boost his attacking options with three forwards - Dwight Gayle, Emmanuel Riviere and Aleksandar Mitrovic - currently in his first-team squad.
United have had a mixed start to the season as they seek to bounce back to the Premier League at the first time of asking, following two defeats with two victories.
Murphy was left out of the Ipswich squad to face Preston on Saturday.
(LC) NEWCASTLE 2 CHELTENHAM 0 (Perez 2)
Darlow, Sterry, Lascelles, Hanley, Gamez, Aarons (24' Gouffran), Shelvey, Colback, Perez, Diame, Mitrovic (38' Gayle)
Subs: Dummett, Hayden, Mbemba, Sels
BRISTOL CITY 0 NEWCASTLE 1 (Gayle)
Sels, Anita, Mbemba, Lascelles, Clark, Ritchie, Hayden (87' Shelvey), Colback, Gouffran, Diame (63' Perez), Gayle (88' Aarons)
Subs: Dummett, Hanley, Darlow, Sterry
NEWCASTLE 4 READING 1 (Hayden, Ritchie (P), Gayle 2)
Sels, Anita, Mbemba, Clark, Dummett, Hayden, Shelvey, Ritchie (90' Aarons), Perez (76' Lascelles), Gouffran (84' Colback), Gayle
Subs: Hanley, Janmaat, Darlow, Armstrong
NEWCASTLE 1 HUDDERSFIELD 2 (Gayle)
Sels, Janmaat (83' Armstrong), Mbemba, Lascelles, Dummett, Anita, Hayden, Shelvey, Aarons (45' Ritchie), Diame (75' Perez), Gayle
Subs: Clark, Colback, Darlow, Gamez
FULHAM 1 NEWCASTLE 0
Sels; Janmaat, Lascelles, Hanley, Dummett; Hayden (Shelvey 77), Colback (Aarons 61); Ritchie, Perez (Armstrong 70), Anita; Gayle.
Subs Mbemba, Darlow, Jesus Gamez, Sterry.
NEWCASTLE 3 VITESSE ARNHEM 2 (Leerdam (og), Gayle, Colback)
Sels; Janmaat (Sterry, 74), Hanley (Gamez, 62), Lascelles, Dummett; Hayden (Saivet, 74), Colback (Shelvey, 62); Anita (Mitrovic, 74), Perez (Armstrong, 62), Ritchie (Aarons, 62); Gayle (Gouffran, 74). Subs not: Darlow, Tiote, Thauvin.
SOUTHEND UTD 0 NEWCASTLE 2 (Anita, Gouffran)
Darlow; Janmaat (Sterry 63), Mbemba (Hanley 63), Lascelles, Dummett; Hayden (Colback 63), Shelvey (Saivet 73); Anita (Thauvin 78), Perez (Mitrovic 73), Aarons (Gouffran 63); Gayle (Armstrong 63).
Sub not used: Sels.
SPORTING LOKEREN 0 NEWCASTLE 4 (Perez 2, Perez, Janmaat, Shelvey)
Sels (Darlow 72); Sterry (Gouffran 63), Mbemba (Saivet 72), Lascelles (Dummett 63), Anita (Gamez 46); Hayden (Shelvey 46), Colback (Tiote 72); Janmaat, Perez (Mitrovic 46), Aarons (Thauvin 63), Gayle (Armstrong 63).
Subs not used: None.
DONCASTER ROVERS 2 NEWCASTLE UTD 2 (Hayden, Perez)
Sels, Janmaat (Sterry, 45), Mbemba (Saivet, 65), Lascelles (Dummett, 45), Colback (Hayden, 45), Anita (Gamez, 45), Ritchie (Gouffran, 45), Aarons (Perez, 45), Shelvey (Wijnaldum, 79), Mitrovic (Gayle, 45), Armstrong (Thauvin, 60).
BOHEMIANS 0 NEWCASTLE 6 (Ritchie, Mitrovic, Gayle, Thauvin, Aarons, Wijnaldum)
Sels, Anita, Lascelles, Mbemba, Sterry, Aarons, Colback, Gouffran, Ritchie, Saivet, Mitrovic.
Subs: Darlow, Gamez, Dummett, Wijnaldum, Shelvey, Hayden, Perez, Gayle, Janmaat, Tiote, Thauvin.