Pearson will be without seven of United's first team squad.
Central midfielders Alan Smith and Nicky Butt are suspended, whole Habib Beye, Abdoulaye Faye, Geremi and Obafemi Martins are away on African Nations Cup duty.
Toon Missing SEVEN For Cup Tie!
Emre is likely to start his first game since Boxing Day, while youngsters Andy Carroll and Kazenga LuaLua could be included in the squad, although Joey Barton will not figure despite his return to training.
NEWCASTLE: Given, Harper, Carr, N'Zogbia, Enrique, Rozehnal, Cacapa, Taylor, Edgar, Milner, Emre, Duff, LuaLua, Viduka, Owen, Martins, Carroll.