Santon returned to the Nerazzurri yesterday, on an initial loan deal, and could make his second debut against Napoli tomorrow.
Marcelo Brozovic is also included in the party, and is likely to make his first start after featuring for 20 minutes at Sassuolo on Sunday.
Inter squad to face Napoli: Handanovic, Carrizo, Berni, Juan Jesus, Vidic, Santon, Dodò, Ranocchia, Donkor, Nagatomo, Kovacic, Guarin, Kuzmanovic, Medel, Obi, Brozovic, Hernanes, Palacio, Icardi, Podolski, Puscas, Shaqiri, Bonazzoli