The move stems from reports on Sky Sports News who understand Southampton's executive chairman Nicola Cortese has handed in his written resignation.
If Cortese's departure is confirmed, Saints boss Mauricio Pochettino's future could be in serious doubt.
Sky sources indicate, however, that Cortese is not in discussion with another club in Italy, despite several media reports.
Cortese considered leaving St Mary's in May of last year after stressing to owner Katharina Liebherr that he was concerned about the future direction of the club.
At the time, Pochettino stressed that his involvement at Southampton was dependent on his chairman remaining at the club.