Shay made his league debut for the Toon against Sheffield Wednesday in August 1997.
Also reaching a milestone is ex-Manchester United midfielder, Nicky Butt, who will be make his 50th appearances in Magpies colours.
If defender Peter Ramage starts, he'll be making his 50th start for the Tyneside club
Unlikely though it maybe, Pavel Srnicek is sat on 199 English League appearances and would reach 200 if he gets onto the pitch, and 150th in a Newcastle jersey.