An army of council workers will begin moving the mountains of rubbish - but the Rangers' fans own reputation, and that of the city's for hosting events - may take longer to clean up.
Police chiefs expressed their disappointment after violent clashes between fans and riot police marred Rangers' attempt to become the first Scottish club to win a European trophy in 25 years.
An underwhelming performance saw the Glasgow side lose 2-0.
Six men, believed to be Rangers supporters, were arrested after a Russian supporter was stabbed inside the stadium.
For hours after the match the centre of the city was a battleground of running battles between Scots supporters and riot police.
Assistant Chief Constable Justine Curran of Greater Manchester Police said: "A minority of thugs have overshadowed what should have been a great occasion."
She added: "I've watched them commit damage, assault my officers and I'm really sickened and disappointed."