Defensive duo James Tomkins (calf) and George McCartney (knee) are again likely to miss out for the Hammers, who could climb to ninth in the Barclays Premier League with a win.
Mark Noble and Joe Cole will be pushing for places in the starting XI after improving their match fitness from the bench in recent weeks.
WEST HAM (from): Jaaskelainen, Henderson, Demel, Reid, O'Brien, Pogatetz, Collins, Potts, Spence, Nolan, O'Neil, Collison, Diame, Noble, Taylor, J Cole, Jarvis, Vaz Te, Carroll, C Cole, Wellington.
Newcastle full-back Mathieu Debuchy will miss the game through suspension.
The France international was sent off for two bookable offences during last weekend's 6-0 drubbing by Liverpool at St James' Park and will sit out the game at Upton Park as a result.
Left-back Massadio Haidara has also been sidelined by a hamstring injury, while keeper Tim Krul (dislocated shoulder), full-back Davide Santon (hamstring) and midfielder Sylvain Marveaux (groin) are all still out, although skipper Fabricio Coloccini could return from a long-term back problem.
NEWCASTLE (from): Elliot, Harper, Simpson, S. Taylor, Coloccini, Williamson, Yanga-Mbiwa, Perch, Tiote, Bigirimana, Cabaye, Anita, Gutierrez, Ben Arfa, Gosling, Obertan, Sissoko, Cisse, Gouffran, Ameobi, Campbell.