The former England international lasted just eight minutes of the 3-1 win and he could be joined on the sidelines by Emre (who scored against the Mackems at St James' Park earlier in the season), who missed out against the Latics with a groin problem.
Shola Ameobi, who damaged his two front teeth in a collision with goalkeeper John Filan and defender Matt Jackson, could be available, while Kieron Dyer suffered no ill effects from his 75 minutes on Saturday.
Sunderland skipper Gary Breen is a major doubt for the Wear-Tyne derby.
Breen limped out of Friday's unexpected draw with Manchester United and, given the swift turnaround, is highly unlikely to have recovered for the clash with Glenn Roeder's men.
Rory Delap also looks certain to miss out after suffering further problems with his broken nose in the warm-up at Old Trafford, while Julio Arca (hamstring) could return.
Sunderland (from): Davis, Carson, Hoyte, Caldwell, Breen, Le Tallec, D Collins, McCartney, Lawrence, Whitehead, Leadbitter, Arca, Miller, Stead, Brown, Kyle, Nosworthy, D Murphy, J Murphy, Bassila, N Collins.
Newcastle (from): Given, Carr, Babayaro, Elliott, Ramage, Moore, Bramble, Solano, N'Zogbia, Shearer, Ameobi, Harper, Boumsong, Clark, Faye, Chopra, Luque.